Viruses have been distributed on CD ROM (for instance, Microsoft shipped Concept, the first (in the wild) macro virus, on a CD ROM called "Windows 95 Software Compatability Test" in 1995). It is wise to scan CD ROMs on arrival for viruses, just like floppies. If the CD ROM has compressed or archived files it is wise to scan it with an anti-virus package which can cope with large amounts of compressed and archived files. If you scan all drives at every boot, though, you may find that this gives you a good incentive to remove CDs from your CD drive before you power down, especially if your scanner isn't set to allow you to break out of a scan. B-)
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